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  2. Pertuzumab - Wikipedia

    en.wikipedia.org/wiki/Pertuzumab

    Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...

  3. FDA Grants Genentech's Perjeta Accelerated Approval for Use ...

    www.aol.com/news/2013-09-30-fda-grants-genen...

    FDA Grants Genentech's Perjeta Accelerated Approval for Use Before Surgery in People With HER2-Positive Early Stage Breast Cancer The Perjeta regimen is the first treatment approved under a new ...

  4. Pertuzumab/trastuzumab/hyaluronidase - Wikipedia

    en.wikipedia.org/wiki/Pertuzumab/trastuzumab/...

    The fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase was approved for medical use in the United States in June 2020. [5] [10]The FDA's approval was based on the results of a non-inferiority study in participants with HER2-positive early breast cancer, which demonstrated the fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase had comparable efficacy and ...

  5. FDA Advisory Committee Recommends Accelerated Approval of ...

    www.aol.com/news/2013-09-12-fda-advisory...

    FDA Advisory Committee Recommends Accelerated Approval of Genentech's Perjeta for Neoadjuvant Use in HER2-Positive Early Stage Breast Cancer The FDA Will Make a Final Decision by October 31 The ...

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  7. Roche's SC Formulation of Perjeta-Herceptin Combo Gets FDA Nod

    www.aol.com/news/roches-sc-formulation-perjeta...

    Roche (RHHBY) receives FDA approval for a fixed-dose combination of Perjeta and Herceptin, Phesgo, plus chemotherapy as a treatment for HER2-positive breast cancer.

  8. Trastuzumab deruxtecan - Wikipedia

    en.wikipedia.org/wiki/Trastuzumab_deruxtecan

    Trastuzumab deruxtecan was approved for medical use in the United States in December 2019, [12] in Japan in March 2020, [14] in the European Union in January 2021, [8] [10] and in Australia in October 2021. [1] It is the first approved therapy by the US Food and Drug Administration (FDA) targeted to people with the HER2-low breast cancer ...

  9. FDA Grants Genentech's Perjeta Regimen Priority Review for ...

    www.aol.com/2013/07/02/fda-grants-genentechs...

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