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MCF-7 cells. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2]
A cancer-associated fibroblast (CAF) (also known as tumour-associated fibroblast; carcinogenic-associated fibroblast; activated fibroblast) is a cell type within the tumor microenvironment that promotes tumorigenic features by initiating the remodelling of the extracellular matrix or by secreting cytokines.
MMTV-PyMT is the model of breast cancer metastasis, in which MMTV-LTR is used to drive the expression of mammary gland specific polyomavirus middle T-antigen, leading to a rapid development of highly metastatic tumors. [45] MMTV-PyMT is the most commonly used model for the study of mammary tumor progression and metastasis.
Metastases can occur several years after the primary breast cancer, although it is sometimes diagnosed at the same time as the primary breast cancer or, rarely, before the primary breast cancer has been diagnosed. [2] Metastatic breast cancer cells frequently differ from the preceding primary breast cancer in properties such as receptor status.
A man who appeared to be homeless was found dead inside a 1 train at the busy Times Square subway station Sunday afternoon after a fellow rider called authorities for help, police and law ...
114783 381983 Ensembl ENSG00000142235 ENSMUSG00000062044 UniProt Q96Q04 Q5XJV6 RefSeq (mRNA) NM_001080434 NM_001388485 NM_001005511 NM_001290990 RefSeq (protein) NP_001073903 NP_001005511 NP_001277919 Location (UCSC) Chr 19: 48.49 – 48.51 Mb Chr 7: 45.43 – 45.45 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Lemur tail kinase 3 is a protein that in humans is encoded by the LMTK3 ...
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