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  2. Phineas Gage - Wikipedia

    en.wikipedia.org/wiki/Phineas_Gage

    Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable: 19 survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior over the remaining 12 years of his life‍—‌effects sufficiently ...

  3. Frontal lobe injury - Wikipedia

    en.wikipedia.org/wiki/Frontal_lobe_injury

    Damage to the frontal lobe can cause increased irritability, which may include a change in mood and an inability to regulate behavior. [1] Particularly, an injury of the frontal lobe could lead to deficits in executive function , such as anticipation, goal selection, planning, initiation, sequencing, monitoring (detecting errors), and self ...

  4. Frontal lobe disorder - Wikipedia

    en.wikipedia.org/wiki/Frontal_lobe_disorder

    Frontal lobe disorder, also frontal lobe syndrome, is an impairment of the frontal lobe of the brain due to disease or frontal lobe injury. [5] The frontal lobe plays a key role in executive functions such as motivation, planning, social behaviour, and speech production. Frontal lobe syndrome can be caused by a range of conditions including ...

  5. Witzelsucht - Wikipedia

    en.wikipedia.org/wiki/Witzelsucht

    Early cases of Witzelsucht observed damage to the mesial-orbital region of the frontal lobe. [6] In general, damage to this area results in puerility, disinhibition, and an inappropriate jocular affect. Subjects with damage to this part of the brain show a preference for gallows humor [citation needed]. The frontal lobes are also involved in ...

  6. Perseveration - Wikipedia

    en.wikipedia.org/wiki/Perseveration

    Perseveration is a common feature of frontal lobe syndrome, as well as neurodegenerative diseases such as progressive supranuclear palsy, corticobasal syndrome and chronic acetogenin poisoning. [8] Perseveration may also refer to the obsessive and highly selective interests of individuals on the autism spectrum.

  7. Frontal lobe - Wikipedia

    en.wikipedia.org/wiki/Frontal_lobe

    This personality change is characteristic of damage to the frontal lobe, and was exemplified in the case of Phineas Gage. The frontal lobe is the same part of the brain that is responsible for executive functions such as planning for the future, judgment, decision-making skills, attention span, and inhibition. These functions can decrease ...

  8. Disinhibition - Wikipedia

    en.wikipedia.org/wiki/Disinhibition

    Disinhibition is a common symptom following brain injury, or lesions, particularly to the frontal lobe and primarily to the orbitofrontal cortex. [4] The neuropsychiatric sequelae following brain injuries could include diffuse cognitive impairment, with more prominent deficits in the rate of information processing, attention, memory, cognitive flexibility, and problem-solving.

  9. Neuropsychological assessment - Wikipedia

    en.wikipedia.org/wiki/Neuropsychological_assessment

    Luria was working with big samples of brain-injured Russian soldiers during and after the second World War. Among many insights from Luria's rehabilitation practice and observations, was the fundamental discovery of the involvement of frontal lobes of the cortex in plasticity, initiation, planning and organization of behaviour.