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The principle of mutability is the notion that any physical property which appears to follow a conservation law may undergo some physical process that violates its conservation. [ 1 ] [ 2 ] [ 3 ] John Archibald Wheeler offered this speculative principle after Stephen Hawking predicted the evaporation of black holes which violates baryon number ...
The undermining of mutationism began almost at once, in 1902, as the statistician Udny Yule analysed Mendel's theory and showed that given full dominance of one allele over another, a 3:1 ratio of alleles would be sustained indefinitely. This meant that the recessive allele could remain in the population with no need to invoke mutation.
The Big Bang Theory logo.. The Big Bang Theory is an American television sitcom created and executively produced by Chuck Lorre and Bill Prady for CBS.Like the name of the series itself (with the exception of the first episode, "Pilot"), episode titles of The Big Bang Theory always start with "The" and resemble the name of a scientific principle, theory or experiment, whimsically referencing a ...
The evolution of sickle cell anemia shows how a heterozygote advantage can affect trait evolution. The Price equation can also be applied to population context dependent traits such as the evolution of sex ratios. Additionally, the Price equation is flexible enough to model second order traits such as the evolution of mutability.
In addition to these counts, data on the mutability and the frequency of the amino acids was obtained. [6] [7] The mutability of an amino acid is the ratio of the number of mutations it is involved in and the number of times it occurs in an alignment. [7] Mutability measures how likely an amino acid is to mutate acceptably.
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Genetic models predict that, in the case of mutation accumulation, elements of fitness, such as reproductive success and survival, will show age-related increases in dominance, homozygous genetic variance and additive variance. Inbreeding depression will also increase with age. This is because these variables are proportional to the equilibrium ...
These include Gini's index of mutability, [13] Simpson's measure of diversity, [14] Bachi's index of linguistic homogeneity, [15] Mueller and Schuessler's index of qualitative variation, [16] Gibbs and Martin's index of industry diversification, [17] Lieberson's index. [18] and Blau's index in sociology, psychology and management studies. [19]
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