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The glycosaminoglycan side chains are polyanionic, which causes adjacent side chains to push each other away and create a "bottle brush", where hyaluronic acid is the stem and the side chains are the bristles. When pressure is exerted on the joint, fluids move between the chondrocytes and synovial fluid, exchanging nutrients. [4]
Intravenous formulations of hyaluronic acid (HA) are available under the trade names Legend and Hyonate. In osteochondral fragmentation models, intravenous HA has been shown to decrease lameness, improve the synovial membrane, and lower protein and prostaglandin E2 levels within joints. [38]
This liquid supplement is a daily, oral version of hyaluronic acid (HA), also called sodium hyaluronate, which had normally been administered by injection. HA is used to promote normal joint function, and to improve joint comfort and performance. LubriSyn is available for horses, humans, and pets. [1]
Other joint medications, like hyaluronic acid and Adequan, may help alleviate the pain if the horse has mild bone spavin. However, they are less useful for treating moderate of severe cases. Nutritional supplements containing MSM, glucosamine, and other ingredients may also help horses with moderate bone spavin.
One group of common alternative treatments are nutraceutical supplements. The most popular of these are joint supplements such as glucosamine, chondroitin, MSM, and hyaluronic acid. Related to joint supplements are various treatments for pain, viewed as alternatives to the common mainstream pain-reducing medications phenylbutazone, and banamine ...
“Hyaluronic acid is a substance naturally found in the body that retains moisture and can hold up to one thousand times its weight in water,” says Celebrity hairstylist Marc Ballance points ...
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