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In contrast to major depression, dementia is a progressive neurodegenerative syndrome involving a pervasive impairment of higher cortical functions resulting from widespread brain pathology. [7] A significant overlap in cognitive and neuropsychological dysfunction in dementia and pseudodementia patients increases the difficulty in diagnosis.
[10] [23] A key aspect found through brain imaging of PCA patients is a loss of grey matter (collections of neuronal cell bodies) in the posterior and occipital temporal cortices within the right hemisphere. [24] For some people with PCA, neuroimaging may not give a clear diagnosis; therefore, careful observation in relation to PCA symptoms can ...
Magnetic resonance imaging (MRI) scans to assess brain structure, connectivity, and the extent of white matter disease; Positron emission tomography (PET) scans to assess how well the brain uses glucose, and the extent of amyloid plaques and tau tangles. Neuropathological examination if a participant dies and has consented to autopsy.
A new study found the biggest risk factors and predictors at 60 for dementia at 80. ... But medical specialists who work with dementia patients say the findings are similar to what they see in ...
Dementia is a devastating condition that impacts up to 10 percent of older adults. And while there's no cure, getting diagnosed early can help patients get on a treatment plan and families prepare ...
Using data from a long-term U.S. survey, it found that newly diagnosed dementia patients are far more likely to act, noting that 25% of respondents sought financial help from children, compared to ...
Further, those with brain damage from trauma or other sources may have worse outcomes with a given burden of LATE-NC in the brain. There is indication from broader dementia research that higher educational attainment and engaging in mentally stimulating activities might delay the onset of clinical symptoms in neurodegenerative diseases.
The diagnostic criteria for depression in Alzheimer disease specify that it requires only 3 of the possible symptoms for major depressive disorder (MDD), rather than the 5 required to diagnose MDD itself, and the symptoms may fluctuate. Therefore, dAD often goes unrecognized within the spectrum of symptoms of Alzheimer's disease. [4]
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