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Acid-citrate-dextrose or acid-citrate-dextrose solution, also known as anticoagulant-citrate-dextrose or anticoagulant-citrate-dextrose solution (and often styled without the hyphens between the coordinate terms, thus acid citrate dextrose or ACD) is any solution of citric acid, sodium citrate, and dextrose in water.
A second sample run with a different anticoagulant such as sodium citrate (blue top tube) to confirm the finding of pseudothrombocytopenia may be requested if there are doubts or concerns. [7] Other alternative anticoagulants are sodium fluoride , CPT ( trisodium citrate , pyridoxal 5′-phosphate and tris ), CTAD (citrate, theophylline ...
Three years later, the introduction by J.F. Loutit and Patrick L. Mollison of acid–citrate–dextrose (ACD) solution, which reduced the volume of anticoagulant, permitted transfusions of greater volumes of blood and allowed longer-term storage. Carl Walter and W.P. Murphy Jr. introduced the plastic bag for blood collection in 1950.
Formulations include plain sodium citrate, acid-citrate-dextrose, and more. Oxalate has a mechanism similar to that of citrate. It is the anticoagulant used in fluoride/oxalate tubes to determine glucose and lactate levels. The fluoride inhibits glycolysis, which can throw off blood sugar measurements. Citrate/fluoride/EDTA tubes work better in ...
Three years later, the introduction by J.F. Loutit and Patrick L. Mollison of acid-citrate-dextrose (ACD) solution, which reduced the volume of anticoagulant, permitted transfusions of greater volumes of blood and allowed longer-term storage. Carl Walter and W.P. Murphy Jr. introduced the plastic bag for blood collection in 1950.
Potassium oxalate (anticoagulant) [6] Glucose, lactate, [7] toxicology [8] Yellow Acid-citrate-dextrose A (anticoagulant) Tissue typing, DNA studies, HIV cultures Pearlescent ("white") Separating gel and (K 2)EDTA: PCR for adenovirus, toxoplasma and HHV-6: Black Sodium Citrate: Paediatric ESR: QuantiFERON Grey, Green, Yellow, Purple QuantiFERON ...
For example, anticoagulant salts can add extra cations like NH 4 +, Li +, Na + and K + to the sample, [23] or impurities like lead and aluminum. [26] Chelator anticoagulants like EDTA and citrate salts work by binding calcium (see carboxyglutamic acid ), but they may also bind other ions.
[1] [2] It is composed of 2.05% dextrose, 0.8% sodium citrate, 0.055% citric acid, and 0.42% sodium chloride. For usage, an equal volume of blood is gently, but thoroughly, mixed with the solution. This solution is used to study in vitro anti-inflammatory activity of crude drugs by the human red blood cell stabilization method. [3]