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  2. Robert C. Randall - Wikipedia

    en.wikipedia.org/wiki/Robert_C._Randall

    Randall successfully used a medical necessity defense when he was charged with illegal possession of cannabis to treat his glaucoma. The case, United States v. Randall (1976), is "The first successful articulation of the medical necessity defense in the history of the common law, and indeed, the first case to extend the necessity defense to the ...

  3. Blurred vision - Wikipedia

    en.wikipedia.org/wiki/Blurred_vision

    Some glaucomas (e.g. open angle glaucoma) cause gradual loss of vision and some others (e.g. angle closure glaucoma) cause sudden loss of vision. [6] It is one of the leading cause of blindness worldwide. [2] Diabetes: Poorly controlled blood sugar can lead to temporary swelling of the lens of the eye, resulting in blurred vision. While it ...

  4. Ghost cell glaucoma - Wikipedia

    en.wikipedia.org/wiki/Ghost_cell_glaucoma

    Ghost cell glaucoma (GCG) is a type of secondary glaucoma occurs due to long standing vitreous hemorrhage. The rigid and less pliable degenerated red blood cells (ghost cells) block the trabecular meshwork and increase the pressure inside eyes .

  5. Optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Optic_neuropathy

    Consumption can be fatal, or recovery can occur with permanent neurologic and ophthalmologic deficits. While the visual loss is not very common, increased intracranial pressure can cause bilateral optic disc swelling from cerebral edema. A clue to the cause of intoxication is the presence of oxalate crystals in the urine.

  6. 5-HT2A receptor - Wikipedia

    en.wikipedia.org/wiki/5-HT2A_receptor

    One effect of 5-HT 2A receptor activation is a reduction in intraocular pressure, and so 5-HT 2A agonists can be useful for the treatment of glaucoma. This has led to the development of compounds such as AL-34662 that are hoped to reduce pressure inside the eyes but without crossing the blood–brain barrier and producing hallucinogenic side ...

  7. Pilocarpine - Wikipedia

    en.wikipedia.org/wiki/Pilocarpine

    Pilocarpine has been known to cause excessive salivation, sweating, bronchial mucus secretion, bronchospasm, bradycardia, vasodilation, and diarrhea. Eye drops can result in brow ache and chronic use in miosis. It can also cause temporary blurred vision or darkness of vision, temporary shortsightedness, hyphema and retinal detachment.

  8. Glaucoma medication - Wikipedia

    en.wikipedia.org/wiki/Glaucoma_medication

    pigmentation of eyelashes, eyelid skin pigmentation, hyperemia (red eye), flu-like symptoms (joint/muscle pain and headache) Bimatoprost: Lumigan: Increased USO (uveoscleral outflow ) Once daily: blurred vision, eyelid redness, eye discomfort, permanently darken iris, darken/thicken eyelashes Travoprost: Travatan: Increased USO (uveoscleral ...

  9. Pseudoexfoliation syndrome - Wikipedia

    en.wikipedia.org/wiki/Pseudoexfoliation_syndrome

    The buildup of protein clumps can block normal drainage of the eye fluid called the aqueous humor and can cause, in turn, a buildup of pressure leading to glaucoma and loss of vision [3] (pseudoexfoliation glaucoma, exfoliation glaucoma). As worldwide populations become older because of shifts in demography, PEX may become a matter of greater ...

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