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Most men should start getting screened when they reach 50, and Black men, people with a family history of prostate cancer, and others with a higher risk should get screened starting at 40.
Prostate cancer is the second-most frequently diagnosed cancer in men, and the second-most frequent cause of cancer death in men (after lung cancer). [ 2 ] [ 3 ] Around 1.2 million new cases of prostate cancer are diagnosed each year, and over 350,000 people die of the disease, annually. [ 2 ]
There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer. It tends to occur in the peripheral zone of the prostate.
Cancer cells migrate in response to different mediators released by autonomic and sensory fibers. Tumor cells secrete CCL2 and CSF-1 to accumulate endoneurial macrophages and, at the same time, release factors that stimulate perineural invasion. Schwann cells release TGFβ, increasing the aggressiveness of cancer cells through TGFβ-RI.
Prostate cancer is the second leading cause of cancer death in American men (behind lung cancer), killing almost 30,000 annually. Although this sounds grim, the natural course of most prostate ...
September is Prostate Cancer Awareness Month, with almost 269,000 men expected to be diagnosed with the disease this year, according to the American Cancer Society. Prostate cancer is the second ...
For men over 64 with prostate cancer limited to the pelvis, using fewer, larger doses of radiation (hypofractionation) results in similar overall survival rates. [28] The risk of dying from prostate cancer or having acute bladder side effects may be similar to that of longer radiation treatment. [28]
An enlarged prostate doesn’t always cause symptoms, but when it does, they can be annoying. And some men have more trouble than others. A look at the condition, also known as benign prostatic ...
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