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[11] [12] [129] Its most major brand names are Provera as oral tablets and Depo-Provera as an aqueous suspension for intramuscular injection. [ 11 ] [ 12 ] [ 129 ] A formulation of MPA as an aqueous suspension for subcutaneous injection is also available in the United States under the brand name Depo-SubQ Provera 104.
Depot MPA (DMPA) and EC/MPA were developed by Upjohn in the 1960s. [12] [13] DMPA (brand name Depo-Provera) was introduced for use as a progestogen-only injectable contraceptive for the first time outside of the United States in 1969 and was subsequently approved for use in birth control in the United States in 1992.
Medroxyprogesterone acetate (brand names Depo-Provera, Provera, Depo-subQ Provera 104) [4] – 150 mg (intramuscularly) or 104 mg (subcutaneously) every 3 months [3] Norethisterone enanthate (brand names NET EN, Noristerat, Norigest, Doryxas) [5] – 200 mg (intramuscularly) every 2 months [3]
CICs are different from progestogen-only injectable contraceptives (POICs), such as depot medroxyprogesterone acetate (DMPA; brand names Depo-Provera, Depo-SubQ Provera 104) and norethisterone enantate (NETE; brand name Noristerat), which are not combined with an estrogen and are given once every two to three months instead of once a month. [2]
Depot medroxyprogesterone acetate, a birth control medication marketed under the brand name Depo-Provera; 2,2-Dimethoxy-2-phenylacetophenone, a radical initiator; N,N′-Dimethyl-1,3-propanediamine, a cross linking reagent; Dimethylol propionic acid; Des Moines Performing Arts, the organization that operates the Civic Center of Greater Des Moines
More than 3,600 cases of debilitating dog health problems caused by the medication were reported between January 2023 and March 2024, the FDA said in the cautionary letter, published Monday.
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