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Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections. [5] This includes aspergillosis , candidiasis , coccidioidomycosis , histoplasmosis , penicilliosis , and infections by Scedosporium or Fusarium . [ 5 ]
2 Side effects. 3 Chemistry. 4 Mechanism of action. ... with the most common adverse effects being fever, ... or voriconazole. ...
The side effects of oral treatment are significant and people without an infection should not take these drugs. [36] Azoles are the group of antifungals which act on the cell membrane of fungi. They inhibit the enzyme 14-alpha-sterol demethylase, a microsomal CYP, which is required for the biosynthesis of ergosterol for the cytoplasmic membrane.
Blood plasma concentrations may be increased when combined with CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, ritonavir, and voriconazole) possibly leading to more side effects. This has been clinically verified for ketoconazole , which increases lurasidone exposure by a factor of 9, and is also expected for other 3A4 inhibitors such as ...
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Image credits: Green____cat One of the effects that negative news can have on our mental health is increased anxiety and worry. When these feelings are heightened, we may also lack optimism, hope ...
Itraconazole is a relatively well-tolerated drug (although not as well tolerated as fluconazole or voriconazole) and the range of adverse effects it produces is similar to the other azole antifungals: [22] elevated alanine aminotransferase levels are found in 4% of people taking itraconazole
Lighter Side. Politics. Science & Tech. Sports. Weather. 24/7 Help. For premium support please call: ... Its use has been controversial in the past over its potential effects on the environment.