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Split-brain or callosal syndrome is a type of disconnection syndrome when the corpus callosum connecting the two hemispheres of the brain is severed to some degree. It is an association of symptoms produced by disruption of, or interference with, the connection between the hemispheres of the brain.
Treatment for those with lissencephaly is symptomatic and depends on the severity and locations of the brain malformations. Treatment is tailored towards the symptoms of the individual. Therapies for lissencephaly are to deal with the symptoms as the syndrome is congenital. Supportive care may be needed to help with comfort and nursing needs.
Researchers suggest that approximately 40% of children diagnosed with drug-resistant epilepsy have some degree of cortical malformation. [ 1 ] [ 2 ] Lissencephaly (to which pachygyria is most closely linked) is associated with severe mental retardation , epilepsy , and motor disability .
MRI of a child experiencing seizures.There are small foci of grey matter heterotopia in the corpus callosum, deep to the dysplastic cortex. (double arrows) Gray matter heterotopia is a neurological disorder caused by gray matter being located in an atypical location in the brain.
Auditory processing disorder (APD), rarely known as King-Kopetzky syndrome, is a neurodevelopmental disorder affecting the way the brain processes sounds. [2] Individuals with APD usually have normal structure and function of the ear, but cannot process the information they hear in the same way as others do, which leads to difficulties in recognizing and interpreting sounds, especially the ...
Disability is based upon the degree in which the brain is affected. Moderate to severe defects may cause intellectual disability, spastic quadriparesis , athetoid movements, endocrine disorders, epilepsy and other serious conditions; mild brain defects may only cause learning or behavior problems with few motor impairments.
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Gerstmann syndrome is a neurological disorder that is characterized by a constellation of symptoms [1] that suggests the presence of a lesion usually near the junction of the temporal and parietal lobes at or near the angular gyrus.