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After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
Does phenylephrine work? Doctors explain how to choose between cold medicines like Dayquil and Sudafed PE for congestion, runny nose, and other symptoms. This Popular Cold Medicine Doesn't Work ...
Due to its sympathomimetic effects, pseudoephedrine is a vasoconstrictor and pressor agent (increases blood pressure), a positive chronotrope (increases heart rate), and a positive inotrope (increases force of heart contractions). [18] [1] [22] [19] [20] The influence of pseudoephedrine on blood pressure at clinical doses is controversial.
Big pharmaceutical companies like Johnson & Johnson may have to pull products from shelves
As noted by the FDA, the most common symptoms of propylhexedrine overdose are the following: "[r]apid heart rate, agitation, high blood pressure, chest pain, tremor, hallucinations, delusions, confusion, nausea, and vomiting." [13] The use of propylhexedrine products in manners inconsistent with their labeling has proven fatal in some cases.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
But this Nov. 7 proposal doesn't immediately take oral phenylephrine off the market. The public has six months to comment on the proposed order and to provide any additional data for the FDA to ...
Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12] Avoid use during pregnancy as it may cause vasoconstriction of uterine arteries thus reducing fetal blood supply. [14] Zyrtec-D, an example of combination therapy. Combination therapy with antihistamines
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