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Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis , acute pain in adults, rheumatoid arthritis , psoriatic arthritis , ankylosing spondylitis , painful menstruation , and juvenile rheumatoid ...
In the CLASS trial which compared Celebrex 800 mg/day to ibuprofen 2400 mg/day and diclofenac 150 mg/day for osteoarthritis or rheumatoid arthritis for six months, Celebrex was associated with significantly fewer upper gastrointestinal complications (0.44% vs. 1.27%, p = 0.04), with no significant difference in incidence of cardiovascular ...
In people with heart failure, NSAIDs increase mortality risk (hazard ratio) by approximately 1.2–1.3 for naproxen and ibuprofen, 1.7 for rofecoxib and celecoxib, and 2.1 for diclofenac. [ 68 ] On 9 July 2015, the Food and Drug Administration (FDA) toughened warnings of increased heart attack and stroke risk associated with nonsteroidal anti ...
People with headaches often take over-the-counter (OTC) medications, like acetaminophen or ibuprofen, to "abort" the headache, according to Healthline. Click Here To Sign Up For Our Health Newsletter.
To highlight this concern, the doctors and editors of Best Buy Drugs publish drug-safety reports to draw attention to the adverse effects and risks of prescription drugs, such as Celebrex and Alli. The reports are created by the Best Buy Drugs team and an independent academic group, Research on Adverse Drug Events and Reports (RADAR) , devoted ...
Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names including Advil, Motrin, and Nurofen.
A review that considered berberine’s effects on heart health found some studies supporting this claim, but due to the high risk of bias, the researchers recommended more clinical trials be ...
Commissioned as a publicity stunt by THQ (a video game publisher that has since gone out of business) for Queen Elizabeth II, this gold-plated Wii stands out as a literal gem in gaming history.
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