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  2. Steroid hormone - Wikipedia

    en.wikipedia.org/wiki/Steroid_hormone

    The role of endocytosis in steroid hormone transport is not well understood and is under further investigation. In order for steroid hormones to cross the lipid bilayer of cells, they must overcome energetic barriers that would prevent their entering or exiting the membrane. Gibbs free energy is an important concept here. These hormones, which ...

  3. Steroid hormone receptor - Wikipedia

    en.wikipedia.org/wiki/Steroid_hormone_receptor

    A steroid hormone receptor is a protein molecule located either within the cell cytoplasm or nucleus that specifically binds to steroid hormones, such as estrogen, progesterone, and testosterone, leading to the activation or suppression of gene expression and subsequent cellular responses. This interaction is crucial for mediating the ...

  4. Hormone receptor - Wikipedia

    en.wikipedia.org/wiki/Hormone_receptor

    Receptors for steroid hormones are usually found within the protoplasm and are referred to as intracellular or nuclear receptors, such as testosterone. [3] Upon hormone binding, the receptor can initiate multiple signaling pathways, which ultimately leads to changes in the behavior of the target cells.

  5. Hormone - Wikipedia

    en.wikipedia.org/wiki/Hormone

    For steroid or thyroid hormones, their receptors are located inside the cell within the cytoplasm of the target cell. These receptors belong to the nuclear receptor family of ligand-activated transcription factors. To bind their receptors, these hormones must first cross the cell membrane. They can do so because they are lipid-soluble.

  6. Peptide hormone - Wikipedia

    en.wikipedia.org/wiki/Peptide_hormone

    Most hormones can be classified as either amino-acid-based hormones (amine, peptide, or protein) or steroid hormones. The former are water-soluble and act on the surface of target cells via second messengers; the latter, being lipid-soluble, move through the plasma membranes of target cells (both cytoplasmic and nuclear) to act within their nuclei.

  7. Steroidogenic acute regulatory protein - Wikipedia

    en.wikipedia.org/wiki/Steroidogenic_acute...

    The steroidogenic acute regulatory protein, commonly referred to as StAR (STARD1), is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones. It is primarily present in steroid-producing cells, including theca cells and luteal cells in the ovary ...

  8. Aldosterone - Wikipedia

    en.wikipedia.org/wiki/Aldosterone

    Steroid receptors are intracellular since steroid hormones are able to cross the cell membrane without a specific transporter. The aldosterone mineralocorticoid receptor (MR) complex binds on the DNA to specific hormone response element , which leads to gene specific transcription .

  9. Cell signaling - Wikipedia

    en.wikipedia.org/wiki/Cell_signaling

    Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells. They are generally intracellular receptors (typically cytoplasmic or nuclear) and initiate signal transduction for steroid hormones which lead to changes in gene