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After the publication of the NIH-run antidepressant clinical trial, clinics began opening in which the intravenous ketamine is given for depression. [5] [6] This practice is an off label use of IV ketamine in the United States, though the intranasal version of esketamine has been approved by the FDA for treatment of depression [5] [7] In 2015 there were about 60 such clinics in the US; the ...
Ketamine is also used to manage pain among large animals. It is the primary intravenous anesthetic agent used in equine surgery, often in conjunction with detomidine and thiopental, or sometimes guaifenesin. [173] Ketamine appears not to produce sedation or anesthesia in snails. Instead, it appears to have an excitatory effect. [174]
2-Fluorodeschloroketamine (also known as 2'-Fl-2-Oxo-PCM, Fluoroketamine and 2-FDCK) is a dissociative anesthetic [1] related to ketamine. Its sale and use as a designer drug has been reported in various countries. [2] [3] [4] It is an analogue of ketamine where the chlorine group has been replaced by fluorine. Due to its recent emergence, the ...
The FDA currently only approves ketamine for short-term sedation and anesthesia. A recent study, published in Nature Medicine , tests an experimental slow-release ketamine tablet that can safely ...
According to the United States Drug Enforcement Administration (DEA), ketamine is a "dissociative anesthetic that has some hallucinogenic effects" and "can induce a state of sedation, immobility ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety , obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [ 1 ]
What is ketamine therapy and why is it used? The Oxford Health NHS Foundation Trust says ketamine therapy can be given to people who have depression which has not responded to other treatments.
2F-NENDCK (CanKet, 2-Fluoro-N-Ethylnordeschloroketamine, 2'-Fluoro-2-Oxo-Phenylcyclohexylethylamine, 2'-Fluoro-2-Oxo-PCE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects presumably similar to those of ketamine.