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Anabolic steroids have a number of medical uses, [1] but are also used by athletes to increase muscle size, strength, and performance. Health risks can be produced by long-term use or excessive doses of AAS.
It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other steroids. [3] It is taken by mouth. [3] Common side effects may include cataracts, bone loss, easy bruising, muscle weakness, and thrush. [3] Other side effects include weight gain, swelling, high blood sugar, increased risk of infection, and ...
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
Diabetes was linked to the concurrent use of mycophenalate mofetil in patients with lupus receiving high-dose steroid therapy; this could be explained by decreased insulin secretion due to elevated beta cell stress. [3] [4] There is an inverse correlation between serum magnesium levels and glycemic control, according to several studies. [5]
Administration of high-dose testosterone in men over a course of weeks can cause an increase in aggression and hypomanic symptoms, though these were seen in only a minority of subjects. [15] Acute high-dose anabolic-androgenic steroid administration in males attenuates endogenous sex hormone production and affects the thyroid hormone axis.
The high doses of testosterone required to increase sexual desire in women may have a significant risk of masculinization with long-term therapy. [41] [40] For this reason, and due to the unknown health effects and safety of testosterone therapy, its use may be inappropriate.
However, anabolic steroids with a very high ratio of anabolic to androgenic action like nandrolone still have significant androgenic effects and can produce symptoms of masculinization like hirsutism and voice deepening in women and children with extended use.
Prednisolone is a corticosteroid, a steroid hormone used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers, electrolyte imbalances and skin conditions. [ 5 ] [ 6 ] Some of these conditions include adrenocortical insufficiency , high blood calcium , rheumatoid arthritis , dermatitis , eye ...