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  2. Macrophage - Wikipedia

    en.wikipedia.org/wiki/Macrophage

    Due to their role in phagocytosis, macrophages are involved in many diseases of the immune system. For example, they participate in the formation of granulomas, inflammatory lesions that may be caused by a large number of diseases. Some disorders, mostly rare, of ineffective phagocytosis and macrophage function have been described, for example ...

  3. Phagocyte - Wikipedia

    en.wikipedia.org/wiki/Phagocyte

    Within one minute the phagosome merges with either a lysosome or a granule to form a phagolysosome. The bacterium is then subjected to an overwhelming array of killing mechanisms [26] and is dead a few minutes later. [25] Dendritic cells and macrophages are not so fast, and phagocytosis can take many hours in these cells.

  4. Phagocytosis - Wikipedia

    en.wikipedia.org/wiki/Phagocytosis

    Phagocytosis (from Ancient Greek φαγεῖν (phagein) 'to eat' and κύτος (kytos) 'cell') is the process by which a cell uses its plasma membrane to engulf a large particle (≥ 0.5 μm), giving rise to an internal compartment called the phagosome. It is one type of endocytosis. A cell that performs phagocytosis is called a phagocyte.

  5. Phagoptosis - Wikipedia

    en.wikipedia.org/wiki/Phagoptosis

    Pathogenic cells such as bacteria can be opsonised by antibodies or complement factors, enabling their phagocytosis and phagoptosis by macrophages and neutrophils. "Aged" erythrocytes and neutrophils, as well as "activated" platelets, neutrophils and T-cells, are thought to be phagocytosed alive by macrophages. Development.

  6. Mononuclear phagocyte system - Wikipedia

    en.wikipedia.org/wiki/Mononuclear_phagocyte_system

    The mononuclear phagocyte system and the monocyte macrophage system refer to two different entities, often mistakenly understood as one. [citation needed] "Reticuloendothelial system" is an older term for the mononuclear phagocyte system, but it is used less commonly now, as it is understood that most endothelial cells are not macrophages. [2]

  7. Phagosome - Wikipedia

    en.wikipedia.org/wiki/Phagosome

    Phagocytosis of a bacterium, showing the formation of phagosome and phagolysosome In cell biology , a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis . Professional phagocytes include macrophages , neutrophils , and dendritic cells (DCs).

  8. Wound healing - Wikipedia

    en.wikipedia.org/wiki/Wound_healing

    Macrophages function in regeneration [26] [27] and are essential for wound healing. [19] They are stimulated by the low oxygen content of their surroundings to produce factors that induce and speed angiogenesis [20] and they also stimulate cells that reepithelialize the wound, create granulation tissue, and lay down a new extracellular matrix. [28]

  9. Humoral immunity - Wikipedia

    en.wikipedia.org/wiki/Humoral_immunity

    Step 1: A macrophage engulfs the pathogen. Step 2: The macrophage then digests the bacterium and presents the pathogen's antigens. Step 3: A T helper cell binds to the macrophage and becomes an activated T helper cell. Step 4: The activated T helper cell binds to a B cell in order to activate the B cell.

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