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  2. Epithelial–mesenchymal transition - Wikipedia

    en.wikipedia.org/wiki/Epithelialmesenchymal...

    Epithelialmesenchymal transition was first recognized as a feature of embryogenesis by Betty Hay in the 1980s. [ 1 ] [ 2 ] EMT, and its reverse process, MET ( mesenchymal-epithelial transition ) are critical for development of many tissues and organs in the developing embryo, and numerous embryonic events such as gastrulation , neural crest ...

  3. Mesenchyme - Wikipedia

    en.wikipedia.org/wiki/Mesenchyme

    Neural mesenchyme soon undergoes a mesenchymalepithelial transition under the influence of WNT6 produced by ectoderm to form somites. [20] These structures will undergo a secondary EMT as the somite tissue migrates later in development to form structural connective tissue such as cartilage and skeletal muscle .

  4. Mesenchymal–epithelial transition - Wikipedia

    en.wikipedia.org/wiki/Mesenchymalepithelial...

    Unlike epithelial cells – which are stationary and characterized by an apico-basal polarity with binding by a basal lamina, tight junctions, gap junctions, adherent junctions and expression of cell-cell adhesion markers such as E-cadherin, [4] mesenchymal cells do not make mature cell-cell contacts, can invade through the extracellular matrix, and express markers such as vimentin ...

  5. Human embryonic development - Wikipedia

    en.wikipedia.org/wiki/Human_embryonic_development

    This ingression sees the cells from the epiblast move into the primitive streak in an epithelial-mesenchymal transition; epithelial cells become mesenchymal stem cells, multipotent stromal cells that can differentiate into various cell types. The hypoblast is pushed out of the way and goes on to form the amnion. The epiblast keeps moving and ...

  6. Bilaminar embryonic disc - Wikipedia

    en.wikipedia.org/wiki/Bilaminar_embryonic_disc

    On day 16, epiblast cells that are next to the primitive streak experience epithelial-to-mesenchymal transformation as they ingress through the primitive streak. The first wave of epiblast cells takes over the hypoblast, which slowly becomes replaced by new cells that eventually constitute the definitive endoderm.

  7. Embryoid body - Wikipedia

    en.wikipedia.org/wiki/Embryoid_body

    As a result of the three-dimensional EB structure, complex morphogenesis occurs during EB differentiation, including the appearance of both epithelial- and mesenchymal-like cell populations, as well as the appearance of markers associated with the epithelial-mesenchymal transition (EMT).

  8. Metaplasia - Wikipedia

    en.wikipedia.org/wiki/Metaplasia

    Metaplasia (from Greek 'change in form') is the transformation of a cell type to another cell type. [1] The change from one type of cell to another may be part of a normal maturation process, or caused by some sort of abnormal stimulus.

  9. Morphogenesis - Wikipedia

    en.wikipedia.org/wiki/Morphogenesis

    Following epithelial-mesenchymal transition, cells can migrate away from an epithelium and then associate with other similar cells in a new location. [11] In plants, cellular morphogenesis is tightly linked to the chemical composition and the mechanical properties of the cell wall.