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Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, [7] and it is an essential drug. [6] It is also used as an antidote to the chemical weapon Lewisite . Nonetheless, because it can have serious adverse effects , researchers have also pursued development of less toxic analogues, [ 7 ] such as succimer .
In the 18th century lead poisoning was fairly frequent on account of the widespread drinking of rum, which was made in stills with a lead component (the "worm"). It was a significant cause of mortality amongst slaves and sailors in the colonial West Indies. [281] [282] Lead poisoning from rum was also noted in Boston. [283]
Curare poisoning can be managed by artificial respiration such as mouth-to-mouth resuscitation. In a study of 29 army volunteers that were paralyzed with curare, artificial respiration managed to keep oxygen saturation always above 85%, [ 37 ] a level at which there is no evidence of altered state of consciousness . [ 38 ]
Sodium calcium edetate (sodium calcium EDTA), also known as edetate calcium disodium among other names, is a medication primarily used to treat lead poisoning, [2] including both short-term and long-term lead poisoning. [3] Sodium calcium edetate came into medical use in the United States in 1953. [3]
Mandatory blood testing and a 2004 law requiring lead paint inspections have paid dividends, contributing to a big drop in the number of reported poisoning cases each year. But for children in many of the poorest parts of the city — areas populated overwhelmingly by minorities and immigrants — the risk of lead poisoning remains stubbornly ...
An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton) , "(medicine) given as a remedy".
The FDA guidance caps lead levels for children younger than 2 at 10 parts per billion for fruits, most vegetables, grain and meat mixtures, yogurts, custards and puddings, and single-ingredient meats.
Lead and cadmium: lead poisoning and cadmium poisoning can lead to gastrointestinal, kidney, and neurological dysfunction. The use of unleaded paints and gas has successfully decreased the number of cases of lead heavy metal poisoning. Nickel, chromium, and cadmium: via metal-DNA interactions, these metals can be carcinogenic. [3]