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Crypt inflammation is known as cryptitis and characterized by the presence of neutrophils between the enterocytes. A severe cryptitis may lead to a crypt abscess. Pathologic processes that lead to Crohn's disease, i.e. progressive intestinal crypt destruction, are associated with branching of the crypts. Causes of crypt branching include:
Enterochromaffin (EC) cells (also known as Kulchitsky cells) are a type of enteroendocrine cell, and neuroendocrine cell.They reside alongside the epithelium lining the lumen of the digestive tract and play a crucial role in gastrointestinal regulation, particularly intestinal motility and secretion. [1]
Paneth cells are found throughout the small intestine and the appendix at the base of the intestinal glands. [2] There is an increase in Paneth cell numbers towards the end of the small intestine. [3] Like the other epithelial cell lineages in the small intestine, Paneth cells originate at the stem cell region near the bottom of the gland. [4]
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system ... Colonic crypts (intestinal glands) ...
In the adult intestine, the crypts of Lieberkühn are the niche for epithelial stem cells and contain all proliferative stem and progenitor cells. Differentiating cells exit the cell cycle and migrate out of the crypts and onto the surface epithelium of the intestine, where they perform their physiological role (e.g., nutrient absorption by enterocytes; mucous secretion by goblet cells) and ...
The intestinal epithelium is the ... cells residing at the base of the intestinal glands produce new epithelial cells which migrate upwards and out of the crypt ...
Focusing on foods that provide soluble (which may soften stool) and insoluble fiber (which helps move bulk through the intestinal system) is the key to reducing constipation. Nutrition experts ...
Essential for stem cell/crypt maintenance. Villus and crypt morphogenesis with Tcf3 via c-Myc: 18948094 [16] 17785439 [17] 17681174 [18] DLL1: Functions as a cis acting element and required for goblet cell differentiation in the Notch inactive colonic epithelia. Notch ligand in intestine. Required for the maintenance of stem and progenitors ...