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2. Acute lymphoblastic leukemia - Wikipedia

   en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

   Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever , easy bleeding or bruising, enlarged lymph nodes , or bone pain. [ 1 ]

3. Blinatumomab - Wikipedia

   en.wikipedia.org/wiki/Blinatumomab

   In July 2014, the FDA granted breakthrough therapy status to blinatumomab for the treatment of acute lymphoblastic leukemia (ALL). [12] In October 2014, Amgen's Biologics License Application for blinatumomab was granted priority review designation by the FDA, thus establishing a deadline of 19 May 2015, for completion of the FDA review process ...

4. T-cell acute lymphoblastic leukemia - Wikipedia

   en.wikipedia.org/wiki/T-cell_acute_lymphoblastic...

   Currently, standard treatment for T-cell acute lymphoblastic leukemia (T-ALL) involves long-term chemotherapy and medication to prevent or treat side effects associated with low white blood cell counts resulting from intensive chemotherapy regimens. The treatment typically occurs in three stages: induction, consolidation, and maintenance. [3]

5. Obecabtagene autoleucel - Wikipedia

   en.wikipedia.org/wiki/Obecabtagene_autoleucel

   Obecabtagene autoleucel, sold under the brand name Aucatzyl, is an anti-cancer medication used for the treatment of acute lymphoblastic leukemia. [1] [2] It is a CD19-directed genetically modified autologous T-cell immunotherapy.

6. Leukemia - Wikipedia

   en.wikipedia.org/wiki/Leukemia

   Subtypes include precursor B acute lymphoblastic leukemia, precursor T acute lymphoblastic leukemia, Burkitt's leukemia, and acute biphenotypic leukemia. While most cases of ALL occur in children, 80% of deaths from ALL occur in adults. [17] Chronic lymphocytic leukemia (CLL) most often affects adults over the age of 55. It sometimes occurs in ...

7. Tisagenlecleucel - Wikipedia

   en.wikipedia.org/wiki/Tisagenlecleucel

   Tisagenlecleucel is indicated for the treatment of those under 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse; or adults with relapsed or refractory (r/r) large B-cell lymphoma after two or more lines of systemic therapy including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, high grade B-cell lymphoma ...