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A series of five children with cerebral folate deficiency and low functioning autism with neurological deficits found a complete reduction of ASD symptoms with the use of folinic acid in a child and substantial improvements in communication in two other children. [7]
Low-functioning autism (LFA) is a degree of autism marked by difficulties with social communication and interaction, challenging behavior, and differences in social or emotional reciprocity. Sleep problems, aggression, stereotypical, and self-injurious behavior are also common symptoms. [ 38 ]
Early intervention in nonspeaking autism emphasizes the critical role of language acquisition before the age of five in predicting positive developmental outcomes; acquiring language before age five is a good indicator of positive child development, that early language development is crucial to educational achievement, employment, independence during adulthood, and social relationships. [2]
Temple Grandin notes that autistic people in low-skilled jobs are more likely to suffer discrimination and suffering at work than those in more rewarding positions, since a certain eccentricity is tolerated in people considered to be talented. [201] The latter may, however, arouse the jealousy of their colleagues. [186]
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Autistic children are less likely to make requests or share experiences and more likely to simply repeat others' words . [105] The CDC estimated in 2015 that around 40% of autistic children do not speak at all. [106] Autistic adults' verbal communication skills largely depend on when and how well speech is acquired during childhood. [102]
The relationship between autism and memory, specifically memory functions in relation to autism spectrum disorder (ASD), is an ongoing topic of research. ASD is a neurodevelopmental disorder characterised by social communication and interaction impairments, along with restricted and repetitive patterns of behavior.
According to the organization Autism Speaks, “speech-language therapy is designed to coordinate the mechanics of speech with the meaning and social use of speech”. [24] People with low-functioning autism may not be able to communicate with spoken words.