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Drugs used in diabetes treat diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin , most GLP-1 receptor agonists ( liraglutide , exenatide , and others), and pramlintide , all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.
While the treatment of hypoglycemia is typically managed with carbohydrate consumption, glucagon injection, or dextrose administration, there are some other treatments available. [3] Medications like diazoxide and octreotide decrease insulin levels, increasing blood glucose levels. [3]
Glucose-elevating agents are medications used to treat hypoglycemia (low blood sugar) by raising blood glucose.In diabetics, hypoglycemia can occur as a result of too much insulin or antidiabetic medication, insufficient food intake, or sudden increase in physical activity or exercise.
Hypoglycemia can also be caused by sulfonylureas in people with type 2 diabetes, although it is far less common because glucose counterregulation generally remains intact in people with type 2 diabetes. Severe hypoglycemia rarely, if ever, occurs in people with diabetes treated only with diet, exercise, or insulin sensitizers.
In those already taking sulphonylureas, there is an increased risk of low blood sugar when taking a medicine in the DPP-4 drug class. [19]Adverse effects include nasopharyngitis, headache, nausea, heart failure, hypersensitivity and skin reactions.
Sulfonylureas, a class of type 2 diabetes medications, are associated with higher risk of impaired awareness of hypoglycemia when used over the long term in a new study.
The medication most commonly may cause stomach upset and symptoms such as diarrhea but in general is well tolerated and has a relatively low chance of causing hypoglycemia. [35] One rare (about 1% chance) but serious side affect of metformin is that it can cause lactic acidosis, usually in patients with poor kidney function . [ 35 ]
A recent study found that a class of medications called SGLT-2 inhibitors—which does not include Ozempic or similar drugs like Zepbound—significantly lowered the risk of dementia in people ...
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