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Hair loss, also known as alopecia or baldness, refers to a loss of hair from part of the head or body. [2] Typically at least the head is involved. [4] The severity of hair loss can vary from a small area to the entire body. [7] Inflammation or scarring is not usually present. [4] Hair loss in some people causes psychological distress. [3]
Radiation induces hair loss through damage to hair follicle stem cell progenitors and alteration of keratin expression. [72] [73] Radiation therapy has been associated with increased mucin production in hair follicles. [74] Studies have suggested electromagnetic radiation as a therapeutic growth stimulant in alopecia. [75]
Pattern hair loss (also known as androgenetic alopecia (AGA) [1]) is a hair loss condition that primarily affects the top and front of the scalp. [2] [3] In male-pattern hair loss (MPHL), the hair loss typically presents itself as either a receding front hairline, loss of hair on the crown and vertex of the scalp, or a combination of both.
Perhaps the most well-known condition to cause hair loss is alopecia, which, Massick explains, “causes your own immune system to attack the hair follicles [so that] the hairs just fall out ...
In alopecia areata, a hair follicle is attacked by the immune system. T-cells swarm the roots, killing the follicle. This causes the hair to fall out and parts of the head to become bald. Alopecia areata is thought to be a systemic autoimmune disorder in which the body attacks its own anagen hair follicles and suppresses or stops hair growth. [22]
Patients with hair loss are at risk for psychological conditions such as increased anxiety and depression. Autoimmune causes of hair loss may put patients at risk for other autoimmune conditions such as hypothyroidism, hyperthyroidism, and vitiligo. [2] Alopecia areata patients may develop insulin resistance putting them at a risk for type 2 ...
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