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There is no level of BNP that perfectly separates patients with and without heart failure. [14]In screening for congenital heart disease in pediatric patients, an NT-proBNP cut-off value of 91 pg/mL could differentiate an acyanotic heart disease (ACNHD) patient from a healthy patient with a sensitivity of 84% and specificity of 42%. [15]
4879 18158 Ensembl ENSG00000120937 ENSMUSG00000029019 UniProt P16860 P40753 RefSeq (mRNA) NM_002521 NM_001287348 NM_008726 RefSeq (protein) NP_002512 NP_002512 NP_001274277 NP_032752 Location (UCSC) Chr 1: 11.86 – 11.86 Mb Chr 4: 148.07 – 148.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone ...
References range may vary with age, sex, race, pregnancy, [10] diet, use of prescribed or herbal drugs and stress. Reference ranges often depend on the analytical method used, for reasons such as inaccuracy , lack of standardisation , lack of certified reference material and differing antibody reactivity . [ 11 ]
Natriuretic peptide-binding receptors and ligand selectivity. [1] A natriuretic peptide is a hormone molecule that plays a crucial role in the regulation of the cardiovascular system. These hormones were first discovered in the 1980s and were found to have very strong diuretic, natriuretic, and vasodilatory effects.
Various laboratory tests (CBC, troponin, BNP, etc.) and imaging studies (chest x-ray, CT scan, ultrasound) are often used to diagnose and classify the cause of pulmonary edema. [4] [5] [6] Treatment is focused on three aspects: improving respiratory function, treating the underlying cause, and
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Atrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac atria that in humans is encoded by the NPPA gene. [5] Natriuretic peptides (ANP, BNP , and CNP ) are a family of hormone/paracrine factors that are structurally related. [ 6 ]
Urine-based pregnancy tests detect hCG in the urine, while blood-based pregnancy tests measure the level of hCG in the blood. [5] The presence of hCG in a woman's body indicates that a fertilized egg has implanted in the uterus and the placenta has started to form. 10 days after fertilization, significant hCG can be detected from woman's blood ...
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