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  2. Tuberous sclerosis - Wikipedia

    en.wikipedia.org/wiki/Tuberous_sclerosis

    Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant genetic disease that causes non-cancerous tumours to grow in the brain and on other vital organs such as the kidneys, heart, liver, eyes, lungs and skin.

  3. Hippocampal sclerosis - Wikipedia

    en.wikipedia.org/wiki/Hippocampal_sclerosis

    Hippocampal sclerosis is the most common brain abnormality in those with temporal lobe epilepsy. [16] Hippocampal sclerosis may occur in children under 2 years of age with 1 instance seen as early as 6 months. [17] About 70% of those evaluated for temporal lobe epilepsy surgery have hippocampal sclerosis.

  4. Cerebral atherosclerosis - Wikipedia

    en.wikipedia.org/wiki/Cerebral_atherosclerosis

    Cerebral atherosclerosis is a type of atherosclerosis where build-up of plaque in the blood vessels of the brain occurs. Some of the main components of the plaques are connective tissue, extracellular matrix, including collagen, proteoglycans, fibronectin, and elastic fibers; crystalline cholesterol, cholesteryl esters, and phospholipids; cells such as monocyte derived macrophages, T ...

  5. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

  6. Lesional demyelinations of the central nervous system

    en.wikipedia.org/wiki/Lesional_demyelinations_of...

    Further breakdown of the blood–brain barrier, in turn cause a number of other damaging effects such as swelling, activation of macrophages, and more activation of cytokines and other destructive proteins. Astrocytes can heal partially the lesion leaving a scar. These scars (sclerae) are the known plaques or lesions usually reported in MS.

  7. Subacute sclerosing panencephalitis - Wikipedia

    en.wikipedia.org/wiki/Subacute_sclerosing_pan...

    Subacute sclerosing panencephalitis (SSPE), also known as Dawson disease, is a rare form of progressive brain inflammation caused by a persistent infection with the measles virus. The condition primarily affects children, teens, and young adults. It has been estimated that about 2 in 10,000 people who get measles will eventually develop SSPE. [1]

  8. Sclerosis (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sclerosis_(medicine)

    Hippocampal sclerosis, a brain damage often seen in individuals with temporal lobe epilepsy. Lichen sclerosus, an inflammatory skin disease that most often affects the vulva and the penis. Multiple sclerosis, or focal sclerosis, [2] is a central nervous system disease which affects coordination.

  9. Nervous system disease - Wikipedia

    en.wikipedia.org/wiki/Nervous_system_disease

    Nervous system diseases, also known as nervous system or neurological disorders, refers to a small class of medical conditions affecting the nervous system.This category encompasses over 600 different conditions, including genetic disorders, infections, cancer, seizure disorders (such as epilepsy), conditions with a cardiovascular origin (such as stroke), congenital and developmental disorders ...