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The trans-acting gene may be on a different chromosome to the target gene, but the activity is via the intermediary protein or RNA that it encodes. Cis-acting elements, on the other hand, do not code for protein or RNA. Both the trans-acting gene and the protein/RNA that it encodes are said to "act in trans" on the target gene.
Trans-acting factors in alternative splicing in mRNA. Alternative splicing is a key mechanism that is involved in gene expression regulation. In the alternative splicing, trans-acting factors such as SR protein, hnRNP and snRNP control this mechanism by acting in trans. SR protein promotes the spliceosome assembly by interacting with snRNP(e.g. U1, U2) and splicing factors(e.g. U2AF65), and it ...
Targeting the rate-limiting initial step is the most efficient in terms of energy costs for the cell. Transcription initiation is regulated by cis-acting elements (enhancers, silencers, isolators) within the regulatory regions of the DNA, and sequence-specific trans-acting factors that act as activators or repressors. [1]
Since this repression occurs between two different protein molecules (intermolecular), it is referred to as a trans-acting process. The protein that is repressed is usually a transcription factor whose function is to up-regulate (i.e., increase) the rate of gene transcription. Hence the net result of transrepression is down regulation of gene ...
Trans-acting siRNA (abbreviated "ta-siRNA" or "tasiRNA") are a class of small interfering RNA (siRNA) that repress gene expression through post-transcriptional gene silencing in land plants. [ 1 ] [ 2 ] [ 3 ] Precursor transcripts from TAS loci are polyadenylated and converted to double-stranded RNA, and are then processed into 21-nucleotide ...
Trans fat, fats containing trans-isomer fatty acids; Trans effect in inorganic chemistry, the increased lability of ligands that are trans to certain other ligands; Trans-acting in molecular biology, an external factor which acts on a molecule; Trans-lunar injection, propulsive maneuver of a spacecraft towards the Moon
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[5] "trans*" becomes a tool of critique for other social movements as well as for oppressive systems. trans* is the avenue through which gender-expansive people (those whose gender identity lies beyond the cisgender experience) explore futures and states of existence beyond the current social structures of identity, emphasizing that their ...