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With paroxysmal nocturnal dyspnea specifically, it is felt while sleeping and causes a person to wake up after about 1 to 2 hours of sleep. [ 3 ] More serious forms of dyspnea can be identified through accompanying findings, such as low blood pressure, decreased respiratory rate, altered mental status, hypoxia, cyanosis, stridor, or unstable ...
Only continuous beat-to-beat BP measurement during an active standing-up maneuver can document this condition. [ 32 ] Classic orthostatic hypotension is frequently characterized by a systolic blood pressure decrease of ≥20 mmHg or diastolic blood pressure decrease of ≥10 mmHg between 30 seconds and 3 min of standing.
Many persons also suggest a weighing feeling on the abdomen. Pain is typically relieved by lying down. It is believed that flank pain on standing that is relieved by lying down is due to movement of the kidney causing intermittent renal tract obstruction. The attack of colic pain is called 'Dietl's crisis' or 'renal paroxysm'. [citation needed]
Rhythmic movement disorder (RMD) is a neurological disorder characterized by repetitive movements of large muscle groups immediately before and during sleep often involving the head and neck. It was independently described first in 1905 by Zappert as jactatio capitis nocturna and by Cruchet as rhythmie du sommeil . [ 1 ]
Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...
Renal arteriography may suggest focally impaired cortical perfusion, while renal biopsy may show interstitial fibrosis and arterial sclerosis. [2] The pain is typically severe, and narcotic therapy is often prescribed as a way to manage chronic pain. Sleep can be difficult because the supine position increases pressure on the flank.
Another underlying sleep disorder, such as narcolepsy, sleep apnea, [8] idiopathic hypersomnia, or restless legs syndrome; Disorders such as clinical depression or atypical depression [medical citation needed] Tumors, head trauma, anemia, kidney failure, hypothyroidism, or an injury to the central nervous system [9] Drug abuse [medical citation ...
Orthostatic intolerance (OI) is the development of symptoms when standing upright that are relieved when reclining. [1] There are many types of orthostatic intolerance. OI can be a subcategory of dysautonomia, a disorder of the autonomic nervous system [2] occurring when an individual stands up. [3]
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