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Nowadays, the MIC is used in antimicrobial susceptibility testing. The MIC is reported by providing the susceptibility interpretation next to each antibiotic. The different susceptibility interpretations are: "S" (susceptible or responding to a standard dosing regimen), "I" (intermediate or requiring increased exposure), and "R" (resistant).
The maximal information coefficient uses binning as a means to apply mutual information on continuous random variables. Binning has been used for some time as a way of applying mutual information to continuous distributions; what MIC contributes in addition is a methodology for selecting the number of bins and picking a maximum over many possible grids.
In practice, the drug concentration is measured at certain discrete points in time and the trapezoidal rule is used to estimate AUC. In pharmacology, the area under the plot of plasma concentration of a drug versus time after dosage (called “area under the curve” or AUC) gives insight into the extent of exposure to a drug and its clearance ...
The broth microdilution method can be used to test the susceptibility of microorganisms to multiple antibiotics at once. [4] Broth microdilution is also highly accurate. The accuracy of its results are comparable to agar dilution, the gold standard of susceptibility testing. Other advantages include the commercial availability of plates, the ...
Segmented linear regression with two segments separated by a breakpoint can be useful to quantify an abrupt change of the response function (Yr) of a varying influential factor (x). The breakpoint can be interpreted as a critical , safe , or threshold value beyond or below which (un)desired effects occur.
The last image we have of Patrick Cagey is of his first moments as a free man. He has just walked out of a 30-day drug treatment center in Georgetown, Kentucky, dressed in gym clothes and carrying a Nike duffel bag. The moment reminds his father of Patrick’s graduation from college, and he takes a picture of his son with his cell phone.
Ryan Reynolds' Canadian citizenship just leveled up.. On Wednesday, Dec. 18, Governor General of Canada Mary Simon announced the list of 88 new appointees to the Order of Canada, which this year ...
It is a common pattern in software testing to send values through test functions and check for correct output. In many cases, in order to thoroughly test functionalities, one needs to test multiple sets of input/output, and writing such cases separately would cause duplicate code as most of the actions would remain the same, only differing in input/output values.