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  2. MammaPrint - Wikipedia

    en.wikipedia.org/wiki/MammaPrint

    In February 2007, the U.S. Food and Drug Administration (FDA) cleared the MammaPrint test for use in the U.S. for lymph node negative breast cancer patients of all ages, ER negative or ER positive, with tumors of less than 5 cm. [19] MammaPrint can be considered as a part of standard of care disease management for early stage breast cancer and ...

  3. Invasive carcinoma of no special type - Wikipedia

    en.wikipedia.org/wiki/Invasive_carcinoma_of_no...

    Patient with locally advanced invasive breast cancer may be offered neoadjuvant systemic therapy and evaluated for tumor response prior to surgery, radiation, and adjuvant therapy. [31] Prophylactic treatment may be an option for those with genetic predisposition to breast cancer.

  4. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

  5. Breast cancer classification - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_classification

    Molecular classification of breast cancer from mRNA expression profiles. DNA microarrays have compared normal cells to breast cancer cells and found differences in the expression of hundreds of genes. Although the significance of many of those genetic differences is unknown, independent analyses by different research groups has found that ...

  6. Radical mastectomy - Wikipedia

    en.wikipedia.org/wiki/Radical_mastectomy

    Radical mastectomy is a surgical procedure that treats breast cancer by removing the breast and its underlying chest muscle (including pectoralis major and pectoralis minor), and lymph nodes of the axilla (armpit). Breast cancer is the most common cancer among women.

  7. Adjuvant therapy - Wikipedia

    en.wikipedia.org/wiki/Adjuvant_therapy

    For example, breast cancer patients of fertile age oftentimes have to weigh the risks and benefits associated with starting an adjuvant therapy regimen after primary treatment. In the some low-risk, low-benefit situations, forgoing adjuvant treatment altogether can be a reasonable decision, but in cases where the risk of metastasis is high ...

  8. Metastatic breast cancer - Wikipedia

    en.wikipedia.org/wiki/Metastatic_breast_cancer

    Breast cancer can metastasize anywhere in body but primarily metastasizes to the bone, lungs, regional lymph nodes, liver and brain, with the most common site being the bone. [4] Treatment of metastatic breast cancer depends on location of the metastatic tumors and includes surgery, radiation, chemotherapy, biological, and hormonal therapy. [5]

  9. TNM staging system - Wikipedia

    en.wikipedia.org/wiki/TNM_staging_system

    G (1–4): the grade of the cancer cells (i.e. they are "low grade" if they appear similar to normal cells, and "high grade" if they appear poorly differentiated) S (0–3): elevation of serum tumor markers; R (0–2): the completeness of the operation (resection-boundaries free of cancer cells or not) Pn (0–1): invasion into adjunct nerves

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