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Trivalent chromium, or chromium(III), is an essential trace mineral in the human diet. [3] In some nutritional supplements, chromium(III) occurs as chromium(III) picolinate (in which chromium is bound to picolinic acid) or chromium(III) nicotinate (in which chromium is bound to nicotinic acid). Nicotinic acid is also known as the B vitamin niacin.
It’s unclear whether children exposed to chromium are at risk for serious health problems, as information on the health effects of eating food contaminated with chromium-6 is limited, the FDA said.
Hexavalent chromium (chromium(VI), Cr(VI), chromium 6) is any chemical compound that contains the element chromium in the +6 oxidation state (thus hexavalent). [1] It has been identified as carcinogenic, which is of concern since approximately 136,000 tonnes (150,000 tons) of hexavalent chromium were produced in 1985. [ 2 ]
While it has no current medical application, the semicarbazide derivative, carbazochrome, is a hemostatic medication. Despite this compound's name, it is unrelated to the element chromium; instead, the ‑chrome suffix indicates a relationship to color, as pure adrenochrome has a deep violet coloration. [1]
California has set a limit for the toxic heavy metal hexavalent chromium in drinking water. Advocates have called for a stricter limit, warning of health risks.
Although the safety of daily chromium doses of up to 1,000 μg has been shown, there are some reports of serious adverse effects by using chromium picolinate, including kidney failure from a six-week course of 600 μg per day and liver disease after using 1,200 to 2,400 μg per day over four to five months. [2]
In a mouse study, researchers found that zolpidem (Ambien), a common sleep aid, could prevent the brain from effectively clearing up 'waste', though it remains unclear whether this could affect ...
Chromium is a member of group 6, of the transition metals. The +3 and +6 states occur most commonly within chromium compounds, followed by +2; charges of +1, +4 and +5 for chromium are rare, but do nevertheless occasionally exist. [29] [30]