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Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin, as the phosphate, an antibiotic; and benzoyl peroxide, an antiseptic. [7] Common side effects include peeling, itching, and dryness of the skin where the gel was ...
Several combination acne treatments containing clindamycin are also marketed, such as single-product formulations of clindamycin with benzoyl peroxide—sold as BenzaClin (Sanofi-Aventis), Duac (a gel form made by Stiefel), and Acanya, among other trade names—and, in the United States, a combination of clindamycin and tretinoin, sold as Ziana ...
The U.S. Food and Drug Administration also has guidance to elucidate dose–response relationships [3] during drug development. Dose response relationships may be used in individuals or in populations. The adage The dose makes the poison reflects how a small amount of a toxin has no significant effect, while a large amount may be fatal. This ...
As a powerful anticholinergic agent, BZ produces a syndrome of effects known as the anticholinergic toxidrome: these include both psychological and physiological effects, with the most incapacitating effect being a state of delirium characterized by cognitive dysfunction, hallucinations, and inability to perform basic tasks.
Cumulative dose is the total dose resulting from repeated exposures of ionizing radiation to an occupationally exposed worker to the same portion of the body, ...
Differences in anti-inflammatory activity between the various individual NSAIDs are small, but there is considerable variation among individual patients in therapeutic response and tolerance to these drugs. About 60% of patients will respond to any NSAID; of the others, those who do not respond to one may well respond to another.
For a structure receiving a very homogeneous dose (100% of the volume receiving exactly 10 Gy, for example) the cumulative DVH will appear as a horizontal line at the top of the graph, at 100% volume as plotted vertically, with a vertical drop at 10 Gy on the horizontal axis. A cumulative DVH from a radiotherapy plan.
Prefix sums are trivial to compute in sequential models of computation, by using the formula y i = y i − 1 + x i to compute each output value in sequence order. However, despite their ease of computation, prefix sums are a useful primitive in certain algorithms such as counting sort, [1] [2] and they form the basis of the scan higher-order function in functional programming languages.