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According to the scientists, it has been assumed that paracetamol was a completely safe drug to use in patients with high blood pressure.
[84] [non-primary source needed] A review of available research has suggested that increase in systolic blood pressure and increased risk of gastrointestinal bleeding associated with chronic paracetamol use shows a degree of dose dependence. [82] The association between paracetamol use and asthma in children has been a matter of controversy. [85]
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
To put this into perspective, some research shows that reducing your systolic blood pressure (top blood pressure reading) by 5 mmHg may lower your risk of cardiovascular events by 10%! The Bottom Line
Alpha-blockers, like prazosin (Minipress®), are typically used to manage high blood pressure. These medications work by blocking the norepinephrine to help prevent blood vessels from tightening ...
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