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The triptan drug class includes 1st generation sumatriptan (which has poor bioavailability), and second generation zolmitriptan. [2] Due to their safety, efficacy and selectivity, triptans are considered first line agents for abortion of migraines. [2] These medications are selective 5-HT 1B/1D receptor agonists with some activity at 5-HT 1F.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
This category contains drugs used to treat and/or prevent migraine headaches. ... This list may not reflect recent changes. Antimigraine drug; 0–9. 2-Bromo-LSD; A.
There are four possible phases of a migraine attack: prodrome, aura, attack and post-drome, the Mayo Clinic explains. Not everyone who gets a migraine attack will experience all four phases.
Side effects are similar to other triptan medications, with the incidence of side effects reportedly being lower than sumatriptan, and side effects occurring rarely except when above 2.5mg. [ 5 ] [ 6 ] The risk of triptan side effects is also in general low, according to a systematic review. [ 7 ]
A migraine attack often causes severe throbbing pain or a pulsing sensation, usually on one side of the head. But migraine attacks are complex, and not everyone will have the same set of symptoms.
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