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Based on the physiological cause of NC, it is projected that the symptoms of NC can worsen over time, with roughly one-third of patients showing signs of improvement with time. [7] For NC patients that develop worse symptoms over time, severe consequences can occur. Over time, untreated NC and LSS can lead to chronic pain and muscle weakness. [13]
Symptoms occur with extension of spine and are relieved with spine flexion. Minimal to zero symptoms when seated or supine. [17] A human vertebral column. Radiculopathy (with or without radicular pain), [20] a neurologic condition in which nerve root dysfunction causes objective signs such as weakness, loss of sensation, and loss of reflex.
On electron microscopy, nemaline bodies within the affected muscle fibers may be found. These bodies are sometimes crisply rod-shaped, but can also be irregular and punctate. The rods may be found alongside atrophic muscle fibers, and may be seen arising from the thickened Z-discs of the sarcolemmae. Affected fibers may be vacuolated or ...
Myelopathy describes any neurologic deficit related to the spinal cord. [1] The most common form of myelopathy in humans, cervical spondylotic myelopathy (CSM), [2] [3] also called degenerative cervical myelopathy, [4] results from narrowing of the spinal canal (spinal stenosis) ultimately causing compression of the spinal cord. [5]
[4] [5] The disease causes progressive muscle loss with weakness, fasciculations, and cramps. Weakness of the bulbar muscles follows causing difficulties in speech and swallowing . Female carriers do not show symptoms. Although there is no cure, supportive intervention can improve mobility and reduce complications.
Its causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. Muscle weakness can also ...
For example, the Mayo Clinic says, you might see: Blind spots, which might be outlined with geometric designs. Shimmering stars or spots. Zigzag lines that slowly float across your vision. Flashes ...
Myelitis is inflammation of the spinal cord which can disrupt the normal responses from the brain to the rest of the body, and from the rest of the body to the brain. . Inflammation in the spinal cord can cause the myelin and axon to be damaged resulting in symptoms such as paralysis and sen
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