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Cefpodoxime is an oral, third-generation cephalosporin antibiotic available in various generic preparations. It is active against both Gram-positive and Gram-negative organisms with notable exceptions including Pseudomonas aeruginosa , Enterococcus , and Bacteroides fragilis .
Cefodizime is a 3rd generation cephalosporin antibiotic with broad spectrum activity against aerobic gram positive and gram negative bacteria. Clinically, it has been shown to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea.
Gonorrhoea or gonorrhea, colloquially known as the clap, [7] is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. [8] Infection may involve the genitals, mouth, or rectum. [9] Gonorrhea is spread through sexual contact with an infected person, [1] or from a mother to a child during birth. [1]
Gonorrhea is the second most common STI in the U.S. and has developed resistance to all antibiotics used to treat it, except for the recommended combined therapy of an injection of the antibiotic ...
Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare) Inhibits the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription ...
Gram-negative: Third-generation cephalosporins have a broad spectrum of activity and further increased activity against gram-negative organisms. They may be particularly useful in treating hospital-acquired infections , although increasing levels of extended-spectrum beta-lactamases are reducing the clinical utility of this class of antibiotics.
Asymptomatic infection is common in both males and females. [8] [10] Untreated infection may spread to the rest of the body (disseminated gonorrhea infection), especially the joints (septic arthritis). Untreated infection in women may cause pelvic inflammatory disease and possible infertility due to the resulting scarring. [11]
Cefotaxime is the only cephalosporin which has very low toxicity in plants, even at higher concentration (up to 500 mg/L). It is widely used to treat plant tissue infections with Gram-negative bacteria, [20] while vancomycin is used to treat the plant tissue infections with Gram-positive bacteria. [21] [22]
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