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Normal adult: 0.2 [84] 0.5 [84] ng/dL 3.1 [86] ... Standard range Optimal range Unit Lower limit ... Vitamin B 12 (Cobalamin) 130, [129] 160 [130] 700, ...
Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]
Vitamin B 12 was discovered as a result of pernicious anemia, an autoimmune disorder in which the blood has a lower than normal number of red blood cells, due to a deficiency of vitamin B 12. [ 5 ] [ 16 ] The ability to absorb the vitamin declines with age, especially in people over 60.
The prevalence of vitamin B 12 deficiency increased substantially in the elderly, where 31% of the elderly had vitamin B 12 levels below 130 pmol/L. In the most recent NDNS survey conducted between 2008 and 2011, serum vitamin B 12 was measured in 549 adults. [162]
Most adults need 2.4 micrograms of vitamin B12 a day, although the numbers are slightly higher during pregnancy and breastfeeding. Causes of vitamin B12 deficiency There are a few reasons why ...
The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.
“Vitamin B12 is necessary for normal processing of carbs, proteins, ... Again, the daily recommended dietary allowance of vitamin B12 for most adults is 2.4 micrograms, stretching up to 2.6 and ...
Deficiencies of Vitamin B 12 or folate produce a macrocytic anemia (large cell anemia) in which the RDW is elevated in roughly two-thirds of all cases. However, a varied size distribution of red blood cells is a hallmark of iron deficiency anemia, and as such shows an increased RDW in virtually all cases.
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