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Normal reference range of RDW-CV in human red blood cells is 11.5–15.4%. [ 2 ] [ 1 ] If anemia is observed, RDW test results are often used together with mean corpuscular volume (MCV) results to determine the possible causes of the anemia.
A reference range is usually defined as the set of values 95 percent of the normal population falls within ... Levels of estradiol (the main ... (RDW) 11.5 [15] 14.5
Mean corpuscular volume (MCV) is the average volume of a red blood cell and is calculated by dividing the hematocrit (Hct) by the concentration of red blood cell count. [citation needed] = [] Normal range: 80–100 fL (femtoliter)
A low RDW has no clinical significance, but an elevated RDW represents increased variation in red blood cell size, a condition known as anisocytosis. [118] Anisocytosis is common in nutritional anemias such as iron deficiency anemia and anemia due to vitamin B12 or folate deficiency, while people with thalassemia may have a normal RDW. [118]
Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is commonly found in anemia and other blood conditions. False diagnostic flagging may be triggered on a complete blood count by an elevated WBC count, agglutinated RBCs, RBC fragments, giant platelets or platelet clumps due to anisocytosis.
Red blood cell distribution width (RDW): Increased (normal range: 11–15%). The spherocytes create variation in the size of the red blood cells on average, thus expanding the distribution. Red blood cell count (RBC): Sometimes increased early (normal range males: 4.3–5.9 million/mm 3; normal range females: 3.5–5.5 million/mm 3). The loss ...
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Prior to the blood transfusion, hematocrit levels are measured to help ensure the transfusion is necessary and safe. [34] A low hematocrit with a low mean corpuscular volume (MCV) with a high red cell distribution width (RDW) suggests a chronic iron-deficient anemia resulting in abnormal hemoglobin synthesis during erythropoiesis. [35]