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This is a list of local anesthetic agents. Not all of these drugs are still used in clinical practice and in research. Some are primarily of historical interest.
Lidocaine was discovered in 1946 and went on sale in 1948. [11] It is on the World Health Organization's List of Essential Medicines. [12] It is available as a generic medication. [8] [13] In 2021, it was the 267th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [14] [15]
Procaine. Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth [1] and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain or Novocaine, in some regions, procaine is referred to ...
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Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
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Tetracaine, also known as amethocaine, is an ester local anesthetic used to numb the eyes, nose, or throat. [2] It may also be applied to the skin before starting intravenous therapy to decrease pain from the procedure. [3] Typically it is applied as a liquid to the area. [2]