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Leukocytosis is a condition in which the white cell count is above the normal range in the blood. [ 1 ] [ 2 ] It is frequently a sign of an inflammatory response , [ 3 ] most commonly the result of infection , but may also occur following certain parasitic infections or bone tumors as well as leukemia .
The clinical signs and symptoms of leukostasis are non-specific but should be suspected in susceptible individuals with leukemia, a high white blood cell count (e.g., over 100,000), and new-onset neurologic or respiratory signs or symptoms. Rales may be heard when listening to the lungs with a stethoscope. [6]
The remaining 50% are due to non-biliary causes. This is because upper abdominal pain and gallstones are both common but are not always related. Non-biliary causes of PCS may be caused by a functional gastrointestinal disorder, such as functional dyspepsia. [6] Chronic diarrhea in postcholecystectomy syndrome is a type of bile acid diarrhea ...
Tachypnea (high respiratory rate), with greater than 20 breaths per minute; or, an arterial partial pressure of carbon dioxide less than 4.3 kPa (32 mmHg) White blood cell count less than 4000 cells/mm³ (4 x 10 9 cells/L) or greater than 12,000 cells/mm³ (12 x 10 9 cells/L); or the presence of greater than 10% immature neutrophils (band forms).
A reticulocyte count is sometimes performed as part of a complete blood count, usually to investigate the cause of a person's anemia or evaluate their response to treatment. Anemia with a high reticulocyte count can indicate that the bone marrow is producing red blood cells at a higher rate to compensate for blood loss or hemolysis, [74] while ...
The anticonvulsant drug, lamotrigine, has been associated with a decrease in white blood cell count. [2] The FDA monograph for metronidazole states that this medication can also cause leukopenia, and the prescriber information suggests a complete blood count, including differential cell count, before and after, in particular, high-dose therapy. [3]
In patients with little to no symptoms, watchful waiting with close observation is generally appropriate. [2] Treatment is recommended when patients become symptomatic or experience one of the following: Dangerous drops in their red blood cell or platelet count; A doubling of their white blood cells in 6 months or less; Significant splenomegaly
Hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.