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An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, [1] opposing diuresis. [2] Its effects are opposite that of a diuretic . The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin .
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In medicine, diuretics are used to treat heart failure, liver cirrhosis, hypertension, influenza, water poisoning, and certain kidney diseases. Some diuretics, such as acetazolamide , help to make the urine more alkaline , and are helpful in increasing excretion of substances such as aspirin in cases of overdose or poisoning.
Use is not recommended in pregnancy or breastfeeding. [2] It works by decreasing the reabsorption of sodium by the kidneys. [1] Torasemide was patented in 1974 and came into medical use in 1993. [3] It is on the World Health Organization's List of Essential Medicines. [4] It is available as a generic medication. [2]
Cardiovascular agents are drugs used to treat diseases associated with the heart or blood vessels. These medications are available for purchase only with a physician’s prescription . They include, but are not limited to, drugs that target hypertension ( antihypertensives ), hyperlipidemia ( antihyperlipidemics ) and blood clotting (blood ...
The thiazide drug class was discovered and developed at Merck and Co. in the 1950s. [3] The first approved drug of this class, chlorothiazide, was marketed under the trade name Diuril beginning in 1958. [3] In most countries, thiazides are the least expensive antihypertensive drugs available. [4]
Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. [4] Furosemide may also be used for the treatment of high blood pressure. [4] It can be taken intravenously or orally. [4]
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs , ranked by sales.
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