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Calcipotriol, also known as calcipotriene, is a synthetic derivative of calcitriol, a form of vitamin D. It is used in the treatment of psoriasis. [1] It is safe for long-term application in psoriatic skin conditions. [medical citation needed] It was patented in 1985 and approved for medical use in 1991. [2]
Treatment of osteoporosis; Prevention of corticosteroid-induced osteoporosis; Calcitriol has been used in an ointment for the treatment of psoriasis, [17] although the vitamin D analogue calcipotriol (calcipotriene) is more commonly used. [18] Calcitriol has also been given by mouth for the treatment of psoriasis [19] and psoriatic arthritis. [20]
The natural, active form of vitamin D is calcitriol (1,25-dihydroxycholecalciferol). This molecule and other naturally occurring forms of vitamin D, including its precursors and metabolites, have been modified to synthesize pharmaceuticals with potentially greater, or selective, therapeutic actions. [1] [2] [3] [4]
From topical creams and phototherapy to steroids and newer injectables called biologics, here's how to choose the right treatment for you.
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...
There are many disease states, medical treatments and medications that put people at risk for vitamin D deficiency. Chronic diseases that increase risk include kidney [35] and liver failure, Crohn’s disease, inflammatory bowel disease and malabsorption syndromes such as cystic fibrosis, and hyper- or hypo-parathyroidism. [24]
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