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Calcipotriol, also known as calcipotriene, is a synthetic derivative of calcitriol, a form of vitamin D. It is used in the treatment of psoriasis. [1] It is safe for long-term application in psoriatic skin conditions. [medical citation needed] It was patented in 1985 and approved for medical use in 1991. [2]
Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
Treatment of osteoporosis; Prevention of corticosteroid-induced osteoporosis; Calcitriol has been used in an ointment for the treatment of psoriasis, [17] although the vitamin D analogue calcipotriol (calcipotriene) is more commonly used. [18] Calcitriol has also been given by mouth for the treatment of psoriasis [19] and psoriatic arthritis. [20]
It is usually prescribed by a general practitioner or dermatologist for the treatment of psoriasis, chronic chapped lips and other severe dry skin conditions because of its ability to reduce excessive skin cell turnover. [1] It is available as an ointment or lotion. It has also been used for vitiligo [5] [6] and Hailey-Hailey disease. [7]
There are many disease states, medical treatments and medications that put people at risk for vitamin D deficiency. Chronic diseases that increase risk include kidney [35] and liver failure, Crohn’s disease, inflammatory bowel disease and malabsorption syndromes such as cystic fibrosis, and hyper- or hypo-parathyroidism. [24]
Vitamin D deficiency: Usually asymptomatic, causes reduce bone density (osteomalacia), rickets, myopathy, and is associated with the development of schizophrenia. It is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D (25(OH)D) in plasma, which is the most accurate measure of stores of vitamin D in the body ...
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