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During a CIS, there is a subacute attack suggestive of demyelination but the patient does not fulfill the criteria for diagnosis of multiple sclerosis. [64] Early treatment can reduce the hazard of conversion to from a first attack to clinically definite multiple sclerosis.
[15] [16] [8] [17] The McDonald criteria are a frequently updated set of guidelines used to establish an MS diagnosis. [18] There is no cure for MS. [19] Current treatments aim to mitigate inflammation and resulting symptoms from acute flares and prevent further attacks with disease-modifying medications.
Unusual types of MS have been described; these include Devic's disease, Balo concentric sclerosis, Schilder's diffuse sclerosis, and Marburg multiple sclerosis. There is debate on whether they are MS variants or different diseases. [31] Multiple sclerosis behaves differently in children, taking more time to reach the progressive stage. [5]
Nearly 2.8 million people live with multiple sclerosis—here’s what you need to know about it, including symptoms, genetic or other risk factors, and when to see a doctor.
Some of these people will develop MS even after several years. Because early initiation of MS disease-modifying therapy is associated with better clinical outcomes, it is important to identify individuals in the subclinical stage of disease and determine if initiation of treatment at this stage is beneficial.
Multiple sclerosis (MS) is a disease of the central nervous system that can cause a range of symptoms. Some people have more mild symptoms while the disease is completely disabling in others.
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