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[312] [313] In one study, 100 mg rectal suppositories of progesterone given five times per day for 9 days resulted in progesterone levels of 5.5 to 29 ng/mL and suppressed circulating testosterone and growth hormone levels by about 50% in men, but did not affect libido or erectile potency in this short treatment period.
Progesterone is used as part of hormone replacement therapy in people who have low progesterone levels, and for other reasons. For purposes of comparison with normal physiological circumstances, luteal phase levels of progesterone are 4 to 30 ng/mL, while follicular phase levels of progesterone are 0.02 to 0.9 ng/mL, menopausal levels are 0.03 to 0.3 ng/mL, and levels of progesterone in men ...
Ethinylestradiol and norethisterone acetate (FemHRT) – 25 μg / 0.5 mg; Estradiol/progesterone (TX-001HR), a combination of estradiol and progesterone in oil-filled capsules, is currently pending approval. [45] Estradiol and norgestimate (Prefest; 1 mg / 90 μg) was previously available in the U.S. but was discontinued.
17α-Acetoxy-6-chloro-1,6-didehydro-progesterone Flugestone acetate (flurogestone acetate) 17α-Acetoxy-9α-fluoro-11β-hydroxyprogesterone Flumedroxone acetate: 17α-Acetoxy-6α-(trifluoromethyl)progesterone Hydroxyprogesterone acetate: 17α-Acetoxyprogesterone Hydroxyprogesterone caproate: 17α-Hexanoxyprogesterone Hydroxyprogesterone heptanoate
Available forms of progesterone [sources 1] [a] Route Form Dose Brand name Availability [b] Oral: Capsule: 100, 200, 300 mg: Prometrium [c] Widespread Tablet (SR) 200, 300, 400 mg: Dubagest SR [c] India Sublingual: Tablet: 10, 25, 50, 100 mg: Luteina [c] Europe [d] Transdermal: Gel [e] 1% (25 mg) Progestogel: Europe Vaginal: Capsule: 100, 200 ...
The brand version, Progesterone, is around $450 for 30 capsules without any discounts or insurance applied. [178] In comparison, Walgreens offers 30 capsules of 100 mg in the generic version for $51 without insurance or coupons applied. The brand name costs around $431 for 30 capsules of 100 mg. [179]
Progesterone is a progestogen, or an agonist of the nuclear progesterone receptors (PRs), the PR-A, PR-B, and PR-C. [1] In one study, progesterone showed EC 50 Tooltip half-maximal effective concentration values of 7.7 nM for the human PR-A and 8.0 nM for the human PR-B. [5] In addition to the PRs, progesterone is an agonist of the membrane progesterone receptors (mPRs), including the mPRα ...
CPA is a progestin (synthetic progestogen), or an agonist of the progesterone receptors, the biological target of progestogens like progesterone. [ 17 ] [ 4 ] It also acts as an antiandrogen , or as an antagonist of the androgen receptor , the biological target of androgens like testosterone and dihydrotestosterone .