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5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis, largely to activate glucose and fatty acid uptake and oxidation when cellular energy is low.
AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming ...
The STK11/LKB1 gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumour suppressor.. LKB1 is a primary upstream kinase of adenosine monophosphate-activated protein kinase (), a necessary element in cell metabolism that is required for maintaining energy homeostasis.
AMPK may refer to: AMP-activated protein kinase, an enzyme (acetyl-CoA carboxylase) kinase, an enzyme This page was last edited on 15 May 2022, at ...
In 1950 the next generation of tactical trucks were being developed. Sizes were rationalized, with 1 ⁄ 4 and 3 ⁄ 4-ton 4x4s and 2 + 1 ⁄ 2, 5, and 10-ton 6x6s. Trucks were military standard designs, 6x6 trucks used common cabs and similar fender and hood styles. [14]
A daytime running lamp (DRL, also daytime running light) is an automotive lighting and bicycle lighting device on the front of a road going motor vehicle or bicycle. [1] It is automatically switched on when the vehicle's handbrake has been pulled down, when the vehicle is in gear , or when the engine is started, emitting white, yellow , or ...
Often used by utility vehicles such as construction vehicles, garbage trucks, semi-trucks amber marker lights and semi-trucks with big and long trailers, snow plows, funeral escorts and hearses, security patrol vehicles, postal vehicles or other vehicles which may be stopped or moving slower than the flow of traffic.
A truck with a bucket-like cargo area which the front can be raised, hinging on the rear, allowing the load to slide ("dump") out of the cargo area. Often a straight truck, semi-trailers are also common. Flatbeds and refuse container trucks can often "dump", but are rarely called that. [3] Eighteen-wheeler