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  2. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]

  3. Evolutionary approaches to depression - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_approaches_to...

    One reason depression is thought to be a pathology is that it causes so much psychic pain and distress. However, physical pain is also very distressful, yet it has an evolved function: to inform the organism that it is being damaged, to motivate it to withdraw from the source of damage, and to learn to avoid such damage-causing circumstances in the future.

  4. Endogenous depression - Wikipedia

    en.wikipedia.org/wiki/Endogenous_depression

    Endogenous depression is an atypical subclass of major depressive disorder (clinical depression). It could be caused by genetic and biological factors. [ 1 ] Endogenous depression occurs due to the presence of an internal (cognitive, biological) stressor instead of an external (social, environmental) stressor. [ 2 ]

  5. Neurotrophic hypothesis of depression - Wikipedia

    en.wikipedia.org/wiki/Neurotrophic_hypothesis_of...

    The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.

  6. Causes of mental disorders - Wikipedia

    en.wikipedia.org/wiki/Causes_of_mental_disorders

    Unlike biological and psychological causes, environmental causes denote a wide range of stressors that individuals experience in everyday life. They are more psychologically than biologically based. [72] Events that evoke feelings of loss are the most likely to cause a mental disorder to develop in an individual. [13]

  7. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...

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