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Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. [1] It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria . [ 1 ] It is active against beta-lactamase -producing organisms such as Staphylococcus aureus , which would otherwise be resistant to most penicillins .
The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins. [1] Some sources identify them with antipseudomonal penicillins, [2] others consider these types to be distinct. [3]
Flucloxacillin has similar pharmacokinetics, antibacterial activity, and indications to dicloxacillin, and the two agents are considered interchangeable. It is reported to have higher, though rare, incidence of severe hepatic adverse effects than dicloxacillin, [ 28 ] but a lower incidence of renal adverse effects.
In medicine, an indication is a valid reason to use a certain test, medication, procedure, or surgery. [1] There can be multiple indications to use a procedure or medication. [2] An indication can commonly be confused with the term diagnosis.
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Ampicillin/flucloxacillin also known as co-fluampicil (), and sold under the tradename Magnapen, is a combination drug of the two β-lactam antibiotics, ampicillin and flucloxacillin, both in equal amounts, available in a capsule and as a liquid, both taken by mouth, and as a formulation which can be given by injection into muscle or vein.
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