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  2. Free-radical theory of aging - Wikipedia

    en.wikipedia.org/wiki/Free-radical_theory_of_aging

    Free radicals can oxidize LDL, and this is a key event in the formation of plaque in arteries, leading to heart disease and stroke. [23] These are examples of how the free-radical theory of aging has been used to neatly "explain" the origin of many chronic diseases. [24]

  3. Oxidative stress - Wikipedia

    en.wikipedia.org/wiki/Oxidative_stress

    Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]

  4. Reactive oxygen species - Wikipedia

    en.wikipedia.org/wiki/Reactive_oxygen_species

    Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination). Effects of ROS on cell metabolism are well documented in a variety of species. [ 20 ] These include not only roles in apoptosis (programmed cell death) but also positive effects such as the induction of host defence [ 37 ] [ 38 ...

  5. Over the Counter: Connecting the dots on the role of free ...

    www.aol.com/news/over-counter-connecting-dots...

    Free radicals have an ominous name and a lot of people misunderstand them, their complex role in our bodies and how to manage them. Over the Counter: Connecting the dots on the role of free ...

  6. Radical (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Radical_(chemistry)

    Radical elimination can be viewed as the reverse of radical addition. In radical elimination, an unstable radical compound breaks down into a spin-paired molecule and a new radical compound. Shown below is an example of a radical elimination reaction, where a benzoyloxy radical breaks down into a phenyl radical and a carbon dioxide molecule. [7]

  7. Mitochondrial theory of ageing - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_theory_of_ageing

    The mitochondrial theory of ageing has two varieties: free radical and non-free radical. The first is one of the variants of the free radical theory of ageing. It was formulated by J. Miquel and colleagues in 1980 [1] and was developed in the works of Linnane and coworkers (1989). [2] The second was proposed by A. N. Lobachev in 1978. [3]

  8. Biological functions of nitric oxide - Wikipedia

    en.wikipedia.org/wiki/Biological_functions_of...

    In alternative fashion, nitrite anions on sun-exposed skin may be photolyzed to free nitric oxide radicals by UVA in sunlight. [19] This mechanism may elicit significant changes to the systemic blood circulation in humans and be exploited for therapeutic purposes. [20] Nasal breathing also produces nitric oxide within the body. [21] [22] [23] [24]

  9. Oxidative phosphorylation - Wikipedia

    en.wikipedia.org/wiki/Oxidative_phosphorylation

    Oxidative phosphorylation in the eukaryotic mitochondrion is the best-understood example of this process. The mitochondrion is present in almost all eukaryotes, with the exception of anaerobic protozoa such as Trichomonas vaginalis that instead reduce protons to hydrogen in a remnant mitochondrion called a hydrogenosome .

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